The work of Takeda Pharmaceutical Company started way back in 1781, when its predecessor began selling traditional Japanese and Chinese remedies. These days, Takeda is one of Asia's largest pharmaceutical companies, making branded prescription drugs that it sells in some 100 countries worldwide. Top-selling products include blood pressure treatment Blopress, diabetes drug Actos, and ulcer medication Prevacid. The company is also a leading maker of over-the-counter medications, such as cold remedies and vitamins, within its home country. Takeda markets many of its products in the US through subsidiary Takeda Pharmaceuticals North America.